Our research focus is three-fold:
1) Better understand the dynamics of molecular and cellular mechanisms in complex networks under healthy as well as diseased conditions; in particular as related to the immune system,
2) Development of technologies to enable more efficient utility of computational systems biology, and
3) Implementation of interactive technologies and computational modeling as a means to improve STEM education.Read more...
Abou-Jaoudé W, Traynard P, Monteiro PT, Saez-Rodriguez J, Helikar T, Thieffry D, Chaouiya C. (2016) Cellular Networks: Logics and Dynamics. Frontiers in Genetics.7:94
Puniya B., Allen L., Hochfelder C., Majumder M., Helikar T. (2016) Systems Perturbation Analysis of a Large Scale Signal Transduction Model Reveals Potentially Influential Candidates for Cancer Therapeutics. Frontiers in Bioengineering and Biotechnology.4:10. doi: 10.3389/fbioe.2016.00010
Helikar T., Cutucache C. E., Herek T., Rogers J. (2015) Integrating interactive computational modeling in biology curricula. PLoS Computational Biology. 11(3): e1004131Read more ...